A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.
Otitis media (OM), inflammation of the middle ear (ME), is a common cause of conductive hearing impairment. Despite the importance of the disease, the aetiology of chronic and recurrent forms of middle ear inflammatory disease remains poorly understood. Studies of the human population suggest that t...
Main Authors: | Michael Crompton, Tom Purnell, Hayley E Tyrer, Andrew Parker, Greg Ball, Rachel E Hardisty-Hughes, Richard Gale, Debbie Williams, Charlotte H Dean, Michelle M Simon, Ann-Marie Mallon, Sara Wells, Mahmood F Bhutta, Martin J Burton, Hilda Tateossian, Steve D M Brown |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-08-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1006969 |
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