Silencing and un-silencing of tetracycline-controlled genes in neurons.

To identify the underlying reason for the controversial performance of tetracycline (Tet)-controlled regulated gene expression in mammalian neurons, we investigated each of the three components that comprise the Tet inducible systems, namely tetracyclines as inducers, tetracycline-transactivator (tT...

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Bibliographic Details
Main Authors: Peixin Zhu, M Isabel Aller, Udo Baron, Sidney Cambridge, Melanie Bausen, Jan Herb, Jürgen Sawinski, Ali Cetin, Pavel Osten, Mark L Nelson, Sebastian Kügler, Peter H Seeburg, Rolf Sprengel, Mazahir T Hasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1888723?pdf=render