Silencing and un-silencing of tetracycline-controlled genes in neurons.
To identify the underlying reason for the controversial performance of tetracycline (Tet)-controlled regulated gene expression in mammalian neurons, we investigated each of the three components that comprise the Tet inducible systems, namely tetracyclines as inducers, tetracycline-transactivator (tT...
Main Authors: | Peixin Zhu, M Isabel Aller, Udo Baron, Sidney Cambridge, Melanie Bausen, Jan Herb, Jürgen Sawinski, Ali Cetin, Pavel Osten, Mark L Nelson, Sebastian Kügler, Peter H Seeburg, Rolf Sprengel, Mazahir T Hasan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1888723?pdf=render |
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