Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.

Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.

Immune responses against intestinal microbiota contribute to the pathogenesis of inflammatory bowel diseases (IBD) and involve CD4(+) T cells, which are activated by major histocompatibility complex class II (MHCII) molecules on antigen-presenting cells (APCs). However, it is largely unexplored how...

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Bibliographic Details
Main Authors: Christoph Thelemann, Remzi Onur Eren, Manuel Coutaz, Jennifer Brasseit, Hanifa Bouzourene, Muriel Rosa, Anais Duval, Christine Lavanchy, Vanessa Mack, Christoph Mueller, Walter Reith, Hans Acha-Orbea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3904943?pdf=render

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http://europepmc.org/articles/PMC3904943?pdf=render

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