Regulation of global gene expression in human Loa loa infection is a function of chronicity.

Human filarial infection is characterized by downregulated parasite-antigen specific T cell responses but distinct differences exist between patients with longstanding infection (endemics) and those who acquired infection through temporary residency or visits to filarial-endemic regions (expatriates...

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Bibliographic Details
Main Authors: Cathy Steel, Sudhir Varma, Thomas B Nutman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3289604?pdf=render