Evaluation of algorithm performance in ChIP-seq peak detection.

Next-generation DNA sequencing coupled with chromatin immunoprecipitation (ChIP-seq) is revolutionizing our ability to interrogate whole genome protein-DNA interactions. Identification of protein binding sites from ChIP-seq data has required novel computational tools, distinct from those used for th...

Full description

Bibliographic Details
Main Authors: Elizabeth G Wilbanks, Marc T Facciotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20628599/pdf/?tool=EBI