Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

SUMMARY The hallmark of tuberculosis (TB) is the formation of granulomas, which are clusters of infected macrophages surrounded by additional macrophages, neutrophils and lymphocytes. Although it has long been thought that granulomas are beneficial for the host, there is evidence that mycobacteria a...

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Main Authors: Esther J. M. Stoop, Tim Schipper, Sietske K. Rosendahl Huber, Alexander E. Nezhinsky, Fons J. Verbeek, Sudagar S. Gurcha, Gurdyal S. Besra, Christina M. J. E. Vandenbroucke-Grauls, Wilbert Bitter, Astrid M. van der Sar
Format: Article
Language:English
Published: The Company of Biologists 2011-07-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/4/526

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http://dmm.biologists.org/content/4/4/526

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