Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex

Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex

A variety of biological differences exist between strains and phylogenetic lineages in the Mycobacterium tuberculosis complex (MTBC). Here, the authors perform RNAseq and methylome analysis of the main clades of the MTBC and show variation in transcriptional profiles is mainly due to mutations in tr...

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Bibliographic Details
Main Authors: Álvaro Chiner-Oms, Michael Berney, Christine Boinett, Fernando González-Candelas, Douglas B. Young, Sebastien Gagneux, William R. Jacobs, Julian Parkhill, Teresa Cortes, Iñaki Comas
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11948-6

Internet

https://doi.org/10.1038/s41467-019-11948-6

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