Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures

Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures

Modification mapping from cDNA data has become a tremendously important approach in epitranscriptomics. So-called reverse transcription signatures in cDNA contain information on the position and nature of their causative RNA modifications. Data mining of, e.g. Illumina-based high-throughput sequenci...

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Bibliographic Details
Main Authors: Lukas Schmidt, Stephan Werner, Thomas Kemmer, Stefan Niebler, Marco Kristen, Lilia Ayadi, Patrick Johe, Virginie Marchand, Tanja Schirmeister, Yuri Motorin, Andreas Hildebrandt, Bertil Schmidt, Mark Helm
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Genetics
Subjects:
RT signature
Watson–Crick face
Galaxy platform
RNA modifications
machine learning
m1A
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00876/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00876/full

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