Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species

Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species

Alzheimer disease (AD) represents an oncoming epidemic that without an effective treatment promises to exact extraordinary human and financial burdens. Studies of pathogenesis are essential for defining targets for discovering disease-modifying treatments. Past studies of AD neuropathology provided...

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Bibliographic Details
Main Authors: Xu-Qiao Chen, William C. Mobley
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer disease
amyloid plaques
neurofibrillary tangles
PET
Down syndrome
Aβ
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00659/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00659/full

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