Interleukin-19 Is a Negative Regulator of Innate Immunity and Critical for Colonic Protection

The cytokine, interleukin (IL)-19, is a member of the IL-10 family that includes IL-20, IL-22, IL-24, and IL-26. Recent studies have shown that IL-19 is produced by keratinocytes, epithelial cells, macrophages, and B-cells. Little is known about the exact biological role of IL-19 in immunological re...

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Bibliographic Details
Main Authors: Yasu-Taka Azuma, Yukiko Matsuo, Hidemitsu Nakajima, George D. Yancopoulos, David M. Valenzuela, Andrew J. Murphy, Margaret Karow, Tadayoshi Takeuchi
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319307741