A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis

A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis

Vibrio parahaemolyticus causes severe gastroenteritis following consumption of contaminated seafood. Global warming has allowed this pathogen to spread worldwide, contributing to recent outbreaks. Clinical isolates are known to harbor an array of virulence factors, including T3SS1 and T3SS2; however...

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Bibliographic Details
Main Authors: Hyungjun Yang, Marcela de Souza Santos, Julia Lee, Hong T. Law, Suneeta Chimalapati, Elena F. Verdu, Kim Orth, Bruce A. Vallance
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
t3ss
vibrio parahaemolyticus
gastroenteritis
in vivo model
pathogenesis
Online Access:https://doi.org/10.1128/mBio.02608-19

Internet

https://doi.org/10.1128/mBio.02608-19

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