Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits

Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits

Abstract Background Increasing evidence suggests that multiple or long-time exposure to general anaesthesia (GA) could be detrimental to cognitive development in young subjects and might also contribute to accelerated neurodegeneration in the elderly. Iron is essential for normal neuronal function,...

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Bibliographic Details
Main Authors: Jing Wu, Jian-Jun Yang, Yan Cao, Huihui Li, Hongting Zhao, Shuofei Yang, Kuanyu Li
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Iron
Ferroptosis
General anaesthesia
Neurotoxicity
Cognition
Online Access:http://link.springer.com/article/10.1186/s12974-020-01777-6

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http://link.springer.com/article/10.1186/s12974-020-01777-6

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