Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells

Abstract Circulating tumor cells (CTCs) are a treasure trove of information regarding the location, type and stage of cancer and are being pursued as both a diagnostic target and a means of guiding personalized treatment. Most isolation technologies utilize properties of the CTCs themselves such as...

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Bibliographic Details
Main Authors: Fabio Fachin, Philipp Spuhler, Joseph M. Martel-Foley, Jon F. Edd, Thomas A. Barber, John Walsh, Murat Karabacak, Vincent Pai, Melissa Yu, Kyle Smith, Henry Hwang, Jennifer Yang, Sahil Shah, Ruby Yarmush, Lecia V. Sequist, Shannon L. Stott, Shyamala Maheswaran, Daniel A. Haber, Ravi Kapur, Mehmet Toner
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-11119-x