Sequencing of Treponema pallidum subsp. pallidum from isolate UZ1974 using Anti-Treponemal Antibodies Enrichment: First complete whole genome sequence obtained directly from human clinical material.

Treponema pallidum subsp. pallidum (TPA) is the infectious agent of syphilis, a disease that infects more than 5 million people annually. Since TPA is an uncultivable bacterium, most of the information on TPA genetics comes from genome sequencing and molecular typing studies. This study presents the...

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Main Authors: Linda Grillová, Lorenzo Giacani, Lenka Mikalová, Michal Strouhal, Radim Strnadel, Christina Marra, Arturo Centurion-Lara, Lucy Poveda, Giancarlo Russo, Darina Čejková, Vladimír Vašků, Jan Oppelt, David Šmajs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6103504?pdf=render