Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

Essential biological systems employ self-correcting mechanisms to maintain cellular homeostasis. Mammalian cell function is dynamically regulated by the interaction of cell surface galectins with branched N-glycans. Here we report that N-glycan branching deficiency triggers the Golgi to generate bio...

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Bibliographic Details
Main Authors: Haik Mkhikian, Christie-Lynn Mortales, Raymond W Zhou, Khachik Khachikyan, Gang Wu, Stuart M Haslam, Patil Kavarian, Anne Dell, Michael Demetriou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Golgi
N-glycosylation
bioequivalence
T cell
galectin
self-correction
Online Access:https://elifesciences.org/articles/14814

Internet

https://elifesciences.org/articles/14814

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