Unveiling Hidden Dynamics of Hippo Signalling: A Systems Analysis

The Hippo signalling pathway has recently emerged as an important regulator of cell apoptosis and proliferation with significant implications in human diseases. In mammals, the pathway contains the core kinases MST1/2, which phosphorylate and activate LATS1/2 kinases. The pro-apoptotic function of t...

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Bibliographic Details
Main Authors: Sung-Young Shin, Lan K. Nguyen
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/7/8/44