Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice

Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice

Abstract Background IL-33, which is known to induce type 2 immune responses via group 2 innate lymphoid cells, has been reported to contribute to neutrophilic airway inflammation in chronic obstructive pulmonary disease. However, its role in the pathogenesis of emphysema remains unclear. Methods We...

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Bibliographic Details
Main Authors: Daisuke Morichika, Akihiko Taniguchi, Naohiro Oda, Utako Fujii, Satoru Senoo, Junko Itano, Arihiko Kanehiro, Yoshiaki Kitaguchi, Masanori Yasuo, Masayuki Hanaoka, Takashi Satoh, Shizuo Akira, Katsuyuki Kiura, Yoshinobu Maeda, Nobuaki Miyahara
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
COPD
HGF
VEGF
Online Access:https://doi.org/10.1186/s12931-021-01705-z

Internet

https://doi.org/10.1186/s12931-021-01705-z

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