Signatures of optimal codon usage in metabolic genes inform budding yeast ecology.

Reverse ecology is the inference of ecological information from patterns of genomic variation. One rich, heretofore underutilized, source of ecologically relevant genomic information is codon optimality or adaptation. Bias toward codons that match the tRNA pool is robustly associated with high gene...

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Bibliographic Details
Main Authors: Abigail Leavitt LaBella, Dana A Opulente, Jacob L Steenwyk, Chris Todd Hittinger, Antonis Rokas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001185