Signatures of optimal codon usage in metabolic genes inform budding yeast ecology.
Reverse ecology is the inference of ecological information from patterns of genomic variation. One rich, heretofore underutilized, source of ecologically relevant genomic information is codon optimality or adaptation. Bias toward codons that match the tRNA pool is robustly associated with high gene...
Main Authors: | Abigail Leavitt LaBella, Dana A Opulente, Jacob L Steenwyk, Chris Todd Hittinger, Antonis Rokas |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-04-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001185 |
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