Potent In Vitro and In Vivo Anticancer Activity of New Bipyridine and Bipyrimidine Gold (III) Dithiocarbamate Derivatives

Potent In Vitro and In Vivo Anticancer Activity of New Bipyridine and Bipyrimidine Gold (III) Dithiocarbamate Derivatives

We synthesized eight new bipyridine and bipyrimidine gold (III) dithiocarbamate-containing complexes (<b>C1</b>&#8211;<b>C8)</b> and tested them in a panel of human cancer cell lines. We used osteosarcoma (MG-63), lung (A549), prostate (PC3 and DU145), breast (MCF-7), ova...

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Bibliographic Details
Main Authors: Muhammad Altaf, Naike Casagrande, Elena Mariotto, Nadeem Baig, Abdel-Nasser Kawde, Giuseppe Corona, Roberto Larcher, Cinzia Borghese, Claudia Pavan, Adam A. Seliman, Donatella Aldinucci, Anvarhusein A. Isab
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
gold (III) complexes
anticancer therapy
cisplatin resistance
doxorubicin resistance
prostate cancer
Online Access:https://www.mdpi.com/2072-6694/11/4/474

Internet

https://www.mdpi.com/2072-6694/11/4/474

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