In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.

In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.

Apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer's disease and has been implicated in the risk for other neurological disorders. The three common ApoE isoforms (ApoE2, E3, and E4) each differ by a single amino acid, with ApoE4 increasing and ApoE2 decreasing the risk o...

Full description

Bibliographic Details
Main Authors: Kristin R Wildsmith, Jacob M Basak, Bruce W Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E Yarasheski, Jennifer X Wang, Kwasi G Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C Sigurdson, Chengjie Xiong, Alison Goate, David M Holtzman, Randall J Bateman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3366983?pdf=render

Internet

http://europepmc.org/articles/PMC3366983?pdf=render

Similar Items