Challenges in EGFRvIII detection in head and neck squamous cell carcinoma.

OBJECTIVE:Head and neck squamous cell carcinoma (HNSCC) accounts for more than 5% of all cancers worldwide. The mortality rate of HNSCC has remained unchanged (approximately 50%) over the last few decades. Ubiquitous overexpression of wild type EGFR in many solid tumors has led to the development of...

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Bibliographic Details
Main Authors: Sarah E Wheeler, Ann Marie Egloff, Lin Wang, C David James, Peter S Hammerman, Jennifer R Grandis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4320077?pdf=render