The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence.

Obstacles to bacterial survival and replication in the cytosol of host cells, and the mechanisms used by bacterial pathogens to adapt to this niche are not well understood. Listeria monocytogenes is a well-studied Gram-positive foodborne pathogen that has evolved to invade and replicate within the h...

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Bibliographic Details
Main Authors: Daniel A Pensinger, Kyle M Boldon, Grischa Y Chen, William J B Vincent, Kyle Sherman, Meng Xiong, Adam J Schaenzer, Emily R Forster, Jörn Coers, Rob Striker, John-Demian Sauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006001