Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential

Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential

The heterogeneity of triple negative breast cancer (TNBC) has led to efforts to further subtype this disease with the hope of identifying new molecular liabilities and drug targets. Furthermore, the finding that TNBC is the most inherently immunogenic type of breast cancer provides the potential for...

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Bibliographic Details
Main Authors: Charles S. Fermaintt, Thilini Peramuna, Shengxin Cai, Leila Takahashi-Ruiz, Jacob Nathaniel Essif, Corena V. Grant, Barry R. O’Keefe, Susan L. Mooberry, Robert H. Cichewicz, April L. Risinger
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
triple negative breast cancer
basal like 2
targeted therapy
immunotherapy
daphnane type diterpenoids
protein kinase C
Online Access:https://www.mdpi.com/2072-6694/13/11/2834

Internet

https://www.mdpi.com/2072-6694/13/11/2834

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