Reprogramming to pluripotency through a somatic stem cell intermediate.

Reprogramming to pluripotency through a somatic stem cell intermediate.

Transcription factor-based reprogramming can lead to the successful switching of cell fates. We have recently reported that mouse embryonic fibroblasts (MEFs) can be directly reprogrammed into induced neural stem cells (iNSCs) after the forced expression of Brn4, Sox2, Klf4, and Myc. Here, we tested...

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Bibliographic Details
Main Authors: Adele G Marthaler, Ulf Tiemann, Marcos J Araúzo-Bravo, Guangming Wu, Holm Zaehres, Jung Keun Hyun, Dong Wook Han, Hans R Schöler, Natalia Tapia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3874029?pdf=render

Internet

http://europepmc.org/articles/PMC3874029?pdf=render

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