Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals

Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals

The South African national treatment programme includes nucleoside reverse transcriptase inhibitors (NRTIs) in both first and second line highly active antiretroviral therapy regimens. Mutations in the RNase H domain have been associated with resistance to NRTIs but primarily in HIV-1 subtype B stud...

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Bibliographic Details
Main Authors: Sinaye Ngcapu, Kristof Theys, Pieter Libin, Vincent C. Marconi, Henry Sunpath, Thumbi Ndung’u, Michelle L. Gordon
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Viruses
Subjects:
HIV-1
RNase H
resistance
mutations
NRTIs
Online Access:https://www.mdpi.com/1999-4915/9/11/330

Internet

https://www.mdpi.com/1999-4915/9/11/330

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