ELISA method to detect α-synuclein oligomers in cell and animal models.

Soluble aggregates of α-synuclein, so-called oligomers, are hypothesized to act as neurotoxic species in Parkinson's disease, Lewy body dementia and multiple systems atrophy, but specific tools to detect these aggregated species are only slowly appearing. We have developed an α-synuclein oligom...

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Bibliographic Details
Main Authors: Louise Berkhoudt Lassen, Emil Gregersen, Anne Kathrine Isager, Cristine Betzer, Rikke Hahn Kofoed, Poul Henning Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5919555?pdf=render