The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence.

The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence.

MicroRNAs (miRNAs) are short 20-22 nucleotide RNA molecules that act as negative regulators of gene expression via translational repression: they have been shown to play a role in development, proliferation, stress response, and apoptosis. The transcriptional regulator LRF (Leukemia/lymphoma Related...

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Bibliographic Details
Main Authors: Laura Poliseno, Letizia Pitto, Marcella Simili, Laura Mariani, Luisa Riccardi, Alessia Ciucci, Milena Rizzo, Monica Evangelista, Alberto Mercatanti, Pier Paolo Pandolfi, Giuseppe Rainaldi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2435600?pdf=render

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