Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.

Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.

BACKGROUND: Recent studies demonstrated an association of STAT4 variants with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating that multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of STAT4 variants on the susceptibil...

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Main Authors: Jürgen Glas, Julia Seiderer, Melinda Nagy, Christoph Fries, Florian Beigel, Maria Weidinger, Simone Pfennig, Wolfram Klein, Jörg T Epplen, Peter Lohse, Matthias Folwaczny, Burkhard Göke, Thomas Ochsenkühn, Julia Diegelmann, Bertram Müller-Myhsok, Darina Roeske, Stephan Brand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2861592?pdf=render

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http://europepmc.org/articles/PMC2861592?pdf=render

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