Kinetic analysis of HER2-binding ABY-025 Affibody molecule using dynamic PET in patients with metastatic breast cancer

Kinetic analysis of HER2-binding ABY-025 Affibody molecule using dynamic PET in patients with metastatic breast cancer

Abstract Background High expression of human epidermal growth factor receptor type 2 (HER2) represents an aggressive subtype of breast cancer. Anti-HER2 treatment requires a theragnostic approach wherein sufficiently high receptor expression in biopsy material is mandatory. Heterogeneity and discord...

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Bibliographic Details
Main Authors: Ali Alhuseinalkhudhur, Mark Lubberink, Henrik Lindman, Vladimir Tolmachev, Fredrik Y. Frejd, Joachim Feldwisch, Irina Velikyan, Jens Sörensen
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:EJNMMI Research
Subjects:
HER2 receptor
Metastatic breast cancer
Affibody
Dynamic PET
Kinetic modelling
Online Access:http://link.springer.com/article/10.1186/s13550-020-0603-9

Internet

http://link.springer.com/article/10.1186/s13550-020-0603-9

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