Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials.

A phenotype recognition model was developed for high throughput screening (HTS) of engineered Nano-Materials (eNMs) toxicity using zebrafish embryo developmental response classified, from automatically captured images and without manual manipulation of zebrafish positioning, by three basic phenotype...

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Bibliographic Details
Main Authors: Rong Liu, Sijie Lin, Robert Rallo, Yan Zhao, Robert Damoiseaux, Tian Xia, Shuo Lin, Andre Nel, Yoram Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323610?pdf=render