Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials

Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials

Abstract Background Gene expression signatures for the prediction of differential survival of patients undergoing anti-cancer therapies are of great interest because they can be used to prospectively stratify patients entering new clinical trials, or to determine optimal treatment for patients in mo...

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Bibliographic Details
Main Authors: Joachim Theilhaber, Marielle Chiron, Jennifer Dreymann, Donald Bergstrom, Jack Pollard
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Bioinformatics
Subjects:
Predictive signature
Predictive biomarker
Gene expression profiling
Multivariate cox models
Metastatic CRC
Metastatic TNBC
Online Access:http://link.springer.com/article/10.1186/s12859-020-03655-7

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http://link.springer.com/article/10.1186/s12859-020-03655-7

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