Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis.

Based on the process of carcinogenesis, carcinogens are classified as either genotoxic or non-genotoxic. In contrast to non-genotoxic carcinogens, many genotoxic carcinogens have been reported to cause tumor in carcinogenic bioassays in animals. Thus evaluating the genotoxicity potential of chemical...

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Bibliographic Details
Main Authors: Won Jun Lee, Sang Cheol Kim, Seul Ji Lee, Jeongmi Lee, Jeong Hill Park, Kyung-Sang Yu, Johan Lim, Sung Won Kwon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3908933?pdf=render