A Personalized CYP2C19 Phenotype-Guided Dosing Regimen of Voriconazole Using a Population Pharmacokinetic Analysis

by Yun Kim, Su-jin Rhee, Wan Beom Park, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee
Published 2019-02-01

A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study.

by Hyewon Chung, Jaeseong Oh, Seo Hyun Yoon, Kyung-Sang Yu, Joo-Youn Cho, Jae-Yong Chung
Published 2018-01-01

Current Bioequivalence Study Designs in South Korea: A Comprehensive Analysis of Bioequivalence Study Reports Between 2013 and 2019

by Ki Young Huh, Eunwoo Kim, Soyoung Lee, Hyounggyoon Yoo, Seonghae Yoon, Kyung-Sang Yu, Jae-Yong Chung
Published 2021-05-01

Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis

by Da Jung Kim, Eun Ju Cho, Kyung-Sang Yu, In-Jin Jang, Jung-Hwan Yoon, Taesung Park, Joo-Youn Cho
Published 2019-10-01

Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity

by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang
Published 2018-09-01

Impact of Vancomycin‐Induced Changes in the Intestinal Microbiota on the Pharmacokinetics of Simvastatin

by Jung Sunwoo, Sang Chun Ji, Andrew HyoungJin Kim, Kyung‐Sang Yu, Joo‐Youn Cho, In‐Jin Jang, SeungHwan Lee
Published 2020-07-01

Population pharmacokinetic model development and its relationship with adverse events of oxcarbazepine in adult patients with epilepsy

by Yoonhyuk Jang, Seonghae Yoon, Tae-Joon Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Kon Chu, Sang Kun Lee
Published 2021-03-01

The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans.

by Jaeseong Oh, SeungHwan Lee, Howard Lee, Joo-Youn Cho, Seo Hyun Yoon, In-Jin Jang, Kyung-Sang Yu, Kyoung Soo Lim
Published 2017-01-01

Population Pharmacokinetic Modelling and Simulation to Determine the Optimal Dose of Nanoparticulated Sorafenib to the Reference Sorafenib

by Ki Young Huh, Sejung Hwang, Sang Yeob Park, Hye Jung Lim, Miryung Jin, Jaeseong Oh, Kyung-Sang Yu, Jae-Yong Chung
Published 2021-04-01

Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis.

by Won Jun Lee, Sang Cheol Kim, Seul Ji Lee, Jeongmi Lee, Jeong Hill Park, Kyung-Sang Yu, Johan Lim, Sung Won Kwon
Published 2014-01-01

An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans

by Anhye Kim, Stephen R. Dueker, Jun Gi Hwang, Jangsoo Yoon, Sang‐Won Lee, Hye Suk Lee, Byung‐Yong Yu, Kyung‐Sang Yu, Howard Lee
Published 2021-01-01

Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients

by Bora Kim, Ji Won Lee, Kyung Taek Hong, Kyung-Sang Yu, In-Jin Jang, Kyung Duk Park, Hee Young Shin, Hyo Seop Ahn, Joo-Youn Cho, Hyoung Jin Kang
Published 2017-05-01

HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in a rat unilateral ureteral...

by Bodokhsuren Tsogbadrakh, Kyung Don Ju, Jinho Lee, Miyeun Han, Junga Koh, Yeonsil Yu, Hajeong Lee, Kyung-Sang Yu, Yun Kyu Oh, Hyo Jin Kim, Curie Ahn, Kook-Hwan Oh
Published 2018-01-01

Targeted busulfan and fludarabine-based conditioning for bone marrow transplantation in chronic granulomatous disease

by Hee Young Ju, Hyoung Jin Kang, Che Ry Hong, Ji Won Lee, Hyery Kim, Sang Hoon Song, Kyung-Sang Yu, In-Jin Jang, June Dong Park, Kyung Duk Park, Hee Young Shin, Joong-Gon Kim, Hyo Seop Ahn
Published 2016-11-01

Home-based virtual reality for chronic pain: protocol for an NIH-supported randomised-controlled trial

by Xiaoyu Liu, Karma McKelvey, Mariko Ishimori, Tom Norris, Brennan Spiegel, Kyung-Sang Yu, Brandon Birckhead, Sam Eberlein, Genie Alvarez, Rebecca Gale, Taylor Dupuy, Katherine Makaroff, Garth Fuller, J T Black, Swamy Venuturupalli, Joseph Tu, Mourad Tighiouart, Lindsey Ross, Mark Vrahas, Itai Danovitch
Published 2021-06-01

Pharmacokinetic equivalence of CT‐P17 to high‐concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects

by Kyung‐Sang Yu, In‐Jin Jang, Hyeong‐Seok Lim, Jang Hee Hong, Min‐Gul Kim, Min Kyu Park, Doo‐Yeoun Cho, Min Soo Park, Jae Yong Chung, Jong‐Lyul Ghim, SeungHwan Lee, Seok Kyu Yoon, In Sun Kwon, Sang Joon Lee, Sung Hyun Kim, Yun Ju Bae, Jung Bin Cha, Daniel E. Furst, Edward Keystone, Jonathan Kay
Published 2021-07-01