Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype

Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype

Hepatic macrophages play an essential role in the granulomatous response to infection with the parasitic helminth Schistosoma mansoni, but the transcriptional changes that underlie this effect are poorly understood. To explore this, we sorted the two previously recognized hepatic macrophage populati...

Full description

Bibliographic Details
Main Authors: Diana Cortes-Selva, Andrew F. Elvington, Andrew Ready, Bartek Rajwa, Edward J. Pearce, Gwendalyn J. Randolph, Keke C. Fairfax
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
schistosomiasis
hepatic macrophages
metabolism
helminth
alternative activation of macrophages
atherosclerosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02580/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02580/full

Similar Items