Dose-to-duration encoding and signaling beyond saturation in intracellular signaling networks.
The cellular response elicited by an environmental cue typically varies with the strength of the stimulus. For example, in the yeast Saccharomyces cerevisiae, the concentration of mating pheromone determines whether cells undergo vegetative growth, chemotropic growth, or mating. This implies that th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-10-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2543107?pdf=render |