Development of IL-17-mediated Delayed-Type Hypersensitivity Is Not Affected by Down-Regulation of IL-25 Expression

Background: IL-25, which is a member of the IL-17 family, induces Th2 cell differentiation and Th2 cytokine production, contributing to induction of Th2-type immune responses and diseases, as a result of which it suppresses Th1- and Th17-type immune responses. Methods: To elucidate the role of IL-25...

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Main Authors: Akina Ishii, Keisuke Oboki, Aya Nambu, Hideaki Morita, Tatsukuni Ohno, Naoki Kajiwara, Ken Arae, Hajime Sudo, Ko Okumura, Hirohisa Saito, Susumu Nakae
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015306523