Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters.

BACKGROUND: Treponema pallidum ssp. pallidum (TPA), the causative agent of syphilis, is a highly clonal bacterium showing minimal genetic variability in the genome sequence of individual strains. Nevertheless, genetically characterized syphilis strains can be clearly divided into two groups, Nichols...

Full description

Bibliographic Details
Main Authors: Helena Pětrošová, Petra Pospíšilová, Michal Strouhal, Darina Čejková, Marie Zobaníková, Lenka Mikalová, Erica Sodergren, George M Weinstock, David Šmajs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769245?pdf=render