Two New <sup>β</sup><i>N</i>-Alkanoyl-5-Hydroxytryptamides with Relevant Antinociceptive Activity

Two New <sup>β</sup><i>N</i>-Alkanoyl-5-Hydroxytryptamides with Relevant Antinociceptive Activity

In this work, we describe a new route for the synthesis and the antinociceptive effects of two new <sup>β</sup><i>N</i>-alkanoyl-5-hydroxytryptamides (named C<sub>20:0</sub>-5HT and C<sub>22:0</sub>-5HT). The antinociceptive activities were evaluated u...

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Bibliographic Details
Main Authors: Jorge Luis Amorim, Fernanda Alves Lima, Ana Laura Macedo Brand, Silvio Cunha, Claudia Moraes Rezende, Patricia Dias Fernandes
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
serotonin amides
<sup>β</sup><i>N</i>-alkanoyl-5-hydroxytryptamides
antinociceptive activity
pain
mechanochemical synthesis
Online Access:https://www.mdpi.com/2227-9059/9/5/455

Internet

https://www.mdpi.com/2227-9059/9/5/455

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