Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency
Abstract CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional knock out (cKO) study revealed reactive gliosis of astrocytes and microglia follo...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-01-01
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| Series: | Molecular Brain |
| Online Access: | https://doi.org/10.1186/s13041-020-00716-z |