Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy.

Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy.

Despite evidence that antitumor immunity can be protective against renal cell carcinoma (RCC), few patients respond objectively to immunotherapy and the disease is fatal once metastases develop. We asked to what extent combinatorial immunotherapy with Adenovirus-encoded murine TNF-related apoptosis-...

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Bibliographic Details
Main Authors: Lyse A Norian, Timothy P Kresowik, Henry M Rosevear, Britnie R James, Timothy R Rosean, Andrew J Lightfoot, Tamara A Kucaba, Christopher Schwarz, Christine J Weydert, Michael D Henry, Thomas S Griffith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3270031?pdf=render

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http://europepmc.org/articles/PMC3270031?pdf=render

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