Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells
Cytokines and chemokines are produced and secreted by a broad range of immune cells including macrophages. Remarkably, little is known about how these inflammatory mediators are released from the various immune cells. Here, the endolysosomal cation channel TRPML2 is shown to play a direct role in ch...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/39720 |