A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.

Bibliographic Details
Main Authors: Tianyi Zhang, Guifeng Wei, Christopher J. Millard, Roman Fischer, Rebecca Konietzny, Benedikt M. Kessler, John W. R. Schwabe, Neil Brockdorff
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06235-9

Internet

https://doi.org/10.1038/s41467-018-06235-9

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