Localized accumulation of Xist RNA in X chromosome inactivation

by Neil Brockdorff
Published 2019-12-01

Local Tandem Repeat Expansion in Xist RNA as a Model for the Functionalisation of ncRNA

by Neil Brockdorff
Published 2018-10-01

The PWWP2A Histone Deacetylase Complex Represses Intragenic Spurious Transcription Initiation in mESCs

by Guifeng Wei, Neil Brockdorff, Tianyi Zhang
Published 2020-11-01

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.

by Mariana de Napoles, Tatyana Nesterova, Neil Brockdorff
Published 2007-09-01

The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation [version 1; peer review: 1 approved, 2 approved with reservations]

by Heather Coker, Guifeng Wei, Benoit Moindrot, Shabaz Mohammed, Tatyana Nesterova, Neil Brockdorff
Published 2020-02-01

Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins.

by Robert J Klose, Sarah Cooper, Anca M Farcas, Neil P Blackledge, Neil Brockdorff
Published 2013-01-01

Transcription initiation activity sets replication origin efficiency in mammalian cells.

by Joana Sequeira-Mendes, Ramón Díaz-Uriarte, Anwyn Apedaile, Derek Huntley, Neil Brockdorff, María Gómez
Published 2009-04-01

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

by Benoit Moindrot, Andrea Cerase, Heather Coker, Osamu Masui, Anne Grijzenhout, Greta Pintacuda, Lothar Schermelleh, Tatyana B. Nesterova, Neil Brockdorff
Published 2015-07-01

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

by Tianyi Zhang, Guifeng Wei, Christopher J. Millard, Roman Fischer, Rebecca Konietzny, Benedikt M. Kessler, John W. R. Schwabe, Neil Brockdorff
Published 2018-09-01

Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.

by Alexander I Shevchenko, Anastasia A Malakhova, Eugeny A Elisaphenko, Nina A Mazurok, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian
Published 2011-01-01

A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements.

by Eugeny A Elisaphenko, Nikolay N Kolesnikov, Alexander I Shevchenko, Igor B Rogozin, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian
Published 2008-06-01

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

by Irene Cantone, Hakan Bagci, Dirk Dormann, Gopuraja Dharmalingam, Tatyana Nesterova, Neil Brockdorff, Claire Rougeulle, Celine Vallot, Edith Heard, Ronan Chaligne, Matthias Merkenschlager, Amanda G. Fisher
Published 2016-08-01

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment

by Sarah Cooper, Martin Dienstbier, Raihann Hassan, Lothar Schermelleh, Jafar Sharif, Neil P. Blackledge, Valeria De Marco, Sarah Elderkin, Haruhiko Koseki, Robert Klose, Andreas Heger, Neil Brockdorff
Published 2014-06-01

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

by Sarah Cooper, Anne Grijzenhout, Elizabeth Underwood, Katia Ancelin, Tianyi Zhang, Tatyana B. Nesterova, Burcu Anil-Kirmizitas, Andrew Bassett, Susanne M. Kooistra, Karl Agger, Kristian Helin, Edith Heard, Neil Brockdorff
Published 2016-11-01

Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development

by David Landeira, Hakan Bagci, Andrzej R. Malinowski, Karen E. Brown, Jorge Soza-Ried, Amelie Feytout, Zoe Webster, Elodie Ndjetehe, Irene Cantone, Helena G. Asenjo, Neil Brockdorff, Thomas Carroll, Matthias Merkenschlager, Amanda G. Fisher
Published 2015-07-01

Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

by Tatyana B. Nesterova, Guifeng Wei, Heather Coker, Greta Pintacuda, Joseph S. Bowness, Tianyi Zhang, Mafalda Almeida, Bianca Bloechl, Benoit Moindrot, Emma J. Carter, Ines Alvarez Rodrigo, Qi Pan, Ying Bi, Chun-Xiao Song, Neil Brockdorff
Published 2019-07-01

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome

by Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker, Neil Brockdorff
Published 2019-01-01

Considerations when investigating lncRNA function in vivo

by Andrew R Bassett, Asifa Akhtar, Denise P Barlow, Adrian P Bird, Neil Brockdorff, Denis Duboule, Anne Ephrussi, Anne C Ferguson-Smith, Thomas R Gingeras, Wilfried Haerty, Douglas R Higgs, Eric A Miska, Chris P Ponting
Published 2014-08-01

MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

by Bryony Graham, Antoine Marcais, Gopuraja Dharmalingam, Thomas Carroll, Chryssa Kanellopoulou, Johannes Graumann, Tatyana B. Nesterova, Anna Bermange, Pijus Brazauskas, Barbara Xella, Skirmantas Kriaucionis, Douglas R. Higgs, Neil Brockdorff, Matthias Mann, Amanda G. Fisher, Matthias Merkenschlager
Published 2016-05-01

FGF4 independent derivation of trophoblast stem cells from the common vole.

by Elena V Grigor'eva, Alexander I Shevchenko, Nina A Mazurok, Eugeny A Elisaphenko, Antonina I Zhelezova, Alexander G Shilov, Pavel A Dyban, Andrey P Dyban, Ekaterina M Noniashvili, Sergey Ya Slobodyanyuk, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian
Published 2009-09-01