Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.

Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.

Apolipoprotein B (ApoB) and ApoE have been shown to participate in the particle formation and the tissue tropism of hepatitis C virus (HCV), but their precise roles remain uncertain. Here we show that amphipathic α-helices in the apolipoproteins participate in the HCV particle formation by using zin...

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Bibliographic Details
Main Authors: Takasuke Fukuhara, Masami Wada, Shota Nakamura, Chikako Ono, Mai Shiokawa, Satomi Yamamoto, Takashi Motomura, Toru Okamoto, Daisuke Okuzaki, Masahiro Yamamoto, Izumu Saito, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004534

Internet

https://doi.org/10.1371/journal.ppat.1004534

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