M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms

M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms

Abstract Background HIV-1 promotes the formation of tunneling nanotubes (TNTs) that connect distant cells, aiding cell-to-cell viral transmission between macrophages. Our recent study suggests that the cellular protein M-Sec plays a role in these processes. However, the timing, mechanism, and to wha...

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Bibliographic Details
Main Authors: Sameh Lotfi, Hesham Nasser, Osamu Noyori, Masateru Hiyoshi, Hiroaki Takeuchi, Yoshio Koyanagi, Shinya Suzu
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Retrovirology
Subjects:
HIV-1
M-sec
Tunneling nanotubes
Cell motility
Online Access:http://link.springer.com/article/10.1186/s12977-020-00528-y

Internet

http://link.springer.com/article/10.1186/s12977-020-00528-y

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