Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

Abstract Aminoacyl-tRNA synthetases (aaRSs) charge tRNAs with their cognate amino acid, an essential precursor step to loading of charged tRNAs onto the ribosome and addition of the amino acid to the growing polypeptide chain during protein synthesis. Because of this important biological function, a...

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Bibliographic Details
Main Authors: Spencer O. Moen, Thomas E. Edwards, David M. Dranow, Matthew C. Clifton, Banumathi Sankaran, Wesley C. Van Voorhis, Amit Sharma, Colin Manoil, Bart L. Staker, Peter J. Myler, Donald D. Lorimer
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00367-6

Internet

https://doi.org/10.1038/s41598-017-00367-6

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