Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma.

Lipocalin 2 (LCN2) is a small secreted protein and its elevated expression has been observed in pancreatic as well as other cancer types. LCN2 has been reported to promote resistance to drug-induced apoptosis, enhance invasion through its physical association with matrix metalloproteinase-9, and pro...

Full description

Bibliographic Details
Main Authors: Lisa Leung, Nikolina Radulovich, Chang-Qi Zhu, Shawna Organ, Bizhan Bandarchi, Melania Pintilie, Christine To, Devang Panchal, Ming Sound Tsao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3464270?pdf=render