The Picornavirus Precursor 3CD has Different Conformational Dynamics Compared to 3C<sup>pro</sup> and 3D<sup>pol</sup> in Functionally Relevant Regions

The Picornavirus Precursor 3CD has Different Conformational Dynamics Compared to 3C<sup>pro</sup> and 3D<sup>pol</sup> in Functionally Relevant Regions

Viruses have evolved numerous strategies to maximize the use of their limited genetic material, including proteolytic cleavage of polyproteins to yield products with different functions. The poliovirus polyprotein 3CD is involved in important protein-protein, protein-RNA and protein-lipid interactio...

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Bibliographic Details
Main Authors: Dennis S. Winston, David D. Boehr
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
picornavirus
poliovirus
polyprotein
virus precursor protein
protease
polymerase
Online Access:https://www.mdpi.com/1999-4915/13/3/442

Internet

https://www.mdpi.com/1999-4915/13/3/442

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